Aging/Search log: Unterschied zwischen den Versionen
Glanz (Diskussion | Beiträge) Aging – freigegebene Erstveröffentlichung 6faa740d2c794e56888ab060b71d3212 43d8e5321ec2 |
Glanz (Diskussion | Beiträge) Aging daily b1de0c2b9a8f49a2a3542c500ab4bae3 43d8e5321ec2 |
||
| (Eine dazwischenliegende Version desselben Benutzers wird nicht angezeigt) | |||
| Zeile 1: | Zeile 1: | ||
__NOTOC__ | __NOTOC__ | ||
<div class="aging-research-world" lang="en" | <div class="aging-research-world aging-journal" lang="en"> | ||
[[Aging| | <div class="aj-masthead"><div class="aj-brand"><span class="aj-monogram">[[Aging|a.]]</span><span>[[Aging|AGING]]<small>RESEARCH IN PROGRESS</small></span></div><div class="aging-languages" role="navigation" aria-label="Sprache / Language"><span class="aging-language" title="Deutsch">[[Altern/Suchprotokoll|🇩🇪]]</span><span class="aging-language" title="English">[[Aging/Search log|🇬🇧]]</span></div></div> | ||
<div class="aj-context"><strong>An evolving AI research project</strong>[[Aging/About the project|Background · goals · methods]]<span>Updated 28 Sep 2026</span></div> | |||
<h1>Search log · 2026-09-28</h1> | |||
<div class="aj-deck">Connect the literature. Challenge assumptions. Understand function.</div> | |||
<div class="aj-article"> | |||
Targeted narrative search of publisher pages, PubMed and PMC; not a systematic review or meta-analysis. Fourteen primary studies: thirteen peer-reviewed and one preprint. First-publication dates in the selected set reach June 2026; later material has not been comprehensively checked. Older mechanistic studies were retained. No original raw-data analysis or experiments were performed. | Targeted narrative search of publisher pages, PubMed and PMC; not a systematic review or meta-analysis. Fourteen primary studies: thirteen peer-reviewed and one preprint. First-publication dates in the selected set reach June 2026; later material has not been comprehensively checked. Older mechanistic studies were retained. No original raw-data analysis or experiments were performed. | ||
| Zeile 29: | Zeile 31: | ||
Next run: new studies, corrections and independent replications; a focused test of the FTL1/redox/DUB hypothesis. Preserve negative searches and conflicting evidence. | Next run: new studies, corrections and independent replications; a focused test of the FTL1/redox/DUB hypothesis. Preserve negative searches and conflicting evidence. | ||
---- | </div> | ||
<div class="aj-section-title"><h2>Continue exploring</h2></div><div class="aj-tiles"><div class="aj-tile"><div class="aj-thumb">[[File:Bovine Pulmonary Artery Endothelial Cells Fluorescent Image.jpg|120px|frameless|link=Aging/Approaches to aging|alt=Fluorescence micrograph of bovine endothelial cells with labeled nuclei, actin and mitochondria.]]</div><div><div class="aj-tile-title">[[Aging/Approaches to aging|Approaches to aging]]</div><div class="aj-tile-desc">Evidence and functional outcomes</div></div></div><div class="aj-tile"><div class="aj-thumb aj-type-thumb">[[Aging/Evidence chain|→]]</div><div><div class="aj-tile-title">[[Aging/Evidence chain|Evidence chain]]</div><div class="aj-tile-desc">How studies generate new questions</div></div></div><div class="aj-tile"><div class="aj-thumb">[[File:DNA double helix.svg|120px|frameless|link=Aging/Research colloquium|alt=Schematic illustration of a DNA double helix.]]</div><div><div class="aj-tile-title">[[Aging/Research colloquium|Research colloquium]]</div><div class="aj-tile-desc">16 foundation assignments + 4 new deep dives</div></div></div></div> | |||
<div class="aj-footer"><div class="aj-brand"><span class="aj-monogram">[[Aging|a.]]</span><span>[[Aging|AGING]]<small>RESEARCH IN PROGRESS</small></span></div><div class="aj-context">[[Aging|Project overview]][[Aging/About the project|Goals & methods]][[Aging/Evidence chain|Evidence chain]]</div><div class="aj-meta">AI-assisted literature research and model building. No laboratory or clinical studies conducted by this project. No personal treatment plans.</div><div class="aj-credits">Image credits · Illustrations, not project data: [https://commons.wikimedia.org/wiki/File:Axolotl_Portrait.jpg Axolotl] — LoKiLeCh ([https://creativecommons.org/licenses/by-sa/3.0/ CC BY-SA 3.0]) · [https://commons.wikimedia.org/wiki/File:XBio_illustration_%E2%80%93_Neuron.png Neuron] — explorebiology (Explore Biology) ([https://creativecommons.org/licenses/by/4.0/ CC BY 4.0]) · [https://commons.wikimedia.org/wiki/File:DNA_double_helix.svg DNA] — Biochemlife ([https://creativecommons.org/licenses/by-sa/4.0/ CC BY-SA 4.0]) · [https://commons.wikimedia.org/wiki/File:Bovine_Pulmonary_Artery_Endothelial_Cells_Fluorescent_Image.jpg Bovine endothelial cells] — Erin Rod ([https://creativecommons.org/licenses/by/4.0/ CC BY 4.0])</div></div> | |||
</div> | </div> | ||
[[Category:Altern / Aging]] | [[Category:Altern / Aging]] | ||
Aktuelle Version vom 28. September 2026, 23:30 Uhr
An evolving AI research projectBackground · goals · methodsUpdated 28 Sep 2026
Search log · 2026-09-28
Connect the literature. Challenge assumptions. Understand function.
Targeted narrative search of publisher pages, PubMed and PMC; not a systematic review or meta-analysis. Fourteen primary studies: thirteen peer-reviewed and one preprint. First-publication dates in the selected set reach June 2026; later material has not been comprehensively checked. Older mechanistic studies were retained. No original raw-data analysis or experiments were performed.
Search queries and follow-up verification
- axolotl regeneration 2026 2025 brain protein ageing regeneration primary study
- brain aging protein 2026 rejuvenation Nature study
- axolotl senescence limb regeneration 2025 2026 study
- site.nature.com brain 2025 aging protein Nature original study
- Shifts in protein aggregate stability 2026
- site.nature.com KLK6 2026 aging brain
- site.science.org brain aging microglia 2026 midlife 3D genome
- Axolotl brain 2022 Science regeneration single cell
- Ageing promotes microglial Published
- FTL1 aging hippocampus 2025 Villeda Nature Aging
- axolotl heart regeneration 2025 2026 original study
- Molecular basis positional memory limb regeneration Otsuki 2025 09036
- FTL1 deubiquitinase neuronal aging USP7 redox
- FTL1 deubiquitinase ferritin aging brain DUB
- "Ftl1" "deubiquitylase"
- "FTL1" "USP7" aging
Title, DOI, date and source access were checked separately. The targeted FTL1/DUB prior-art search did not establish novelty. The June 2026 cardiac study was followed up via PMID 42346394. Press and social sources were not used as outcome evidence. Some PubMed/PMC/Elsevier pages were challenge-protected; source-level access limitations are in the register. Full supplements, all power analyses, conflicts of interest and raw data were not audited. Independent replication was generally not assessed. Clinical intervention studies and trial registers were outside this first mechanistic report; their omission is not an assessment of the clinical field.
Next run: new studies, corrections and independent replications; a focused test of the FTL1/redox/DUB hypothesis. Preserve negative searches and conflicting evidence.
Continue exploring
Evidence and functional outcomes
How studies generate new questions
16 foundation assignments + 4 new deep dives
